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Predicted efficacy and tolerance of different dosage regimens of benzylpenicillin in horses based on a pharmacokinetic study with three IM formulations and one IV formulation

IntroductionBenzylpenicillin (BP) is a first-line antibiotic in horses but there are discrepancies between manufacturers and literature recommendations regarding dosing regimen. Objectives of this study were to evaluate pharmacokinetics and local tolerance of four different formulations of BP in adu...

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Principais autores: Aude A. Ferran, Béatrice B. Roques, Laura Chapuis, Taisuke Kuroda, Marlène Z. Lacroix, Pierre-Louis Toutain, Alain Bousquet-Melou, Elodie A. Lallemand
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-05-01
Serier:Frontiers in Veterinary Science
Fag:
benzylpenicillin
penicillin
horse
PK/PD
pharmacokinetics
tolerance
Online adgang:https://www.frontiersin.org/articles/10.3389/fvets.2024.1409266/full
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