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Hydroxyethylcellulose-Based Hydrogels Containing Liposomes Functionalized with Cell-Penetrating Peptides for Nasal Delivery of Insulin in the Treatment of Diabetes

Liposomes functionalized with cell-penetrating peptides are a promising strategy to deliver insulin through the nasal route. A hydrogel based on hydroxyethylcellulose (HEC) aqueous solution was prepared, followed by a subsequent addition of liposomes containing insulin solution functionalized with t...

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Autori principali: Eliete de Souza Von Zuben, Josimar Oliveira Eloy, Maiara Destro Inácio, Victor Hugo Sousa Araujo, Amanda Martins Baviera, Maria Palmira Daflon Gremião, Marlus Chorilli
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2022-11-01
Serie:Pharmaceutics
Soggetti:
insulin
liposome
cell-penetrating peptide
hydrogel
nasal delivery
antihyperglycemic effect
Accesso online:https://www.mdpi.com/1999-4923/14/11/2492
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