Efficacy and durability of immediate versus delayed single-dose HPV vaccination for persistent infection among young women in Kenya: a randomized, blinded, cross-over clinical trial

Abstract Evidence is needed for single-dose human papillomavirus (HPV) vaccine efficacy (VE) durability to support vaccination guidelines. In this randomized crossover trial (NCT03675256), healthy young women aged 15-20 years, recruited through community-based screening in Kenya, were randomly alloc...

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Main Authors:	Ruanne V. Barnabas, Elizabeth R. Brown, Elizabeth A. Bukusi, Betty Njoroge, Rachel L. Winer, Denise A. Galloway, Imeldah N. Wakhungu, Charlene Biwott, Syovata Kimanthi, Kate B. Heller, Meighan Krows, Susan Morrison, Elena A. Rechkina, Stephen L. Cherne, R. Scott McClelland, Nelly R. Mugo, Maricianah A. Onono
Format:	Artigo
Language:	Inglês
Published:	Nature Portfolio 2026-05-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-026-72654-8
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