Distinct osmoregulatory responses to sodium loading in patients with altered glycosaminoglycan structure: a randomized cross-over trial

Abstract Background By binding to negatively charged polysaccharides called glycosaminoglycans, sodium can be stored in the body—particularly in the skin—without concurrent water retention. Concordantly, individuals with changed glycosaminoglycan structure (e.g. type 1 diabetes (DM1) and hereditary...

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Detalhes bibliográficos

Principais autores:	Eliane F. E. Wenstedt, Jetta J. Oppelaar, Stijn Besseling, Nienke M. G. Rorije, Rik H. G. Olde Engberink, Arie Oosterhof, Toin H. van Kuppevelt, Bert-Jan H. van den Born, Jan Aten, Liffert Vogt
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2021-01-01
coleção:	Journal of Translational Medicine
Assuntos:	Sodium Glycosaminoglycan Osmoregulation Type 1 diabetes Hereditary multiple exostoses Nuclear factor of activated T-cells 5
Acesso em linha:	https://doi.org/10.1186/s12967-021-02700-0
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