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Genistein inhibits the replication of enterovirus A71

BackgroundGenistein, an isoflavone abundant in soybeans and other legumes, has shown antiviral activity against several viruses. Its effects on enteroviruses, particularly EV71—the causative agent of hand, foot, and mouth disease (HFMD)—remain incompletely understood.MethodsIn vitro assays were used...

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Principais autores: Wenbo Huo, Yahong Zhang, Cong Wang, Changrui Huang, Xinhe Zhou, Siyu Liu, Hongying Bai, Xiaoyan Yu, Jinghua Yu
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-04-01
Serier:Frontiers in Pharmacology
Fag:
autophagy
EV71
G2/M arrest
genistein
viral replication
Online adgang:https://www.frontiersin.org/articles/10.3389/fphar.2026.1787050/full
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