Impairment and Restoration of Homeostatic Plasticity in Cultured Cortical Neurons From a Mouse Model of Huntington Disease

Huntington disease (HD) is an inherited neurodegenerative disorder caused by a mutation in the huntingtin gene. The onset of symptoms is preceded by synaptic dysfunction. Homeostatic synaptic plasticity (HSP) refers to processes that maintain the stability of networks of neurons, thought to be requi...

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Principais autores:	Amy I. Smith-Dijak, Wissam B. Nassrallah, Lily Y. J. Zhang, Michal Geva, Michael R. Hayden, Lynn A. Raymond
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2019-05-01
Serija:	Frontiers in Cellular Neuroscience
Teme:	Huntington disease homeostatic synaptic plasticity calcium BDNF
Online dostop:	https://www.frontiersin.org/article/10.3389/fncel.2019.00209/full
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