Perspectives of targeting LILRB1 in innate and adaptive immune checkpoint therapy of cancer

Immune checkpoint blockade is a compelling approach in tumor immunotherapy. Blocking inhibitory pathways in T cells has demonstrated clinical efficacy in different types of cancer and may hold potential to also stimulate innate immune responses. A novel emerging potential target for immune checkpoin...

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Hlavní autoři:	Tobias Zeller, Ira A. Münnich, Roland Windisch, Patricia Hilger, Denis M. Schewe, Andreas Humpe, Christian Kellner
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2023-09-01
Edice:	Frontiers in Immunology
Témata:	LILRB1 (ILT2) macrophages cancer phagocytosis immune checkpoint blockade antibody therapy
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1240275/full
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