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Does hyperglycemia affect arginine metabolites in critically ill patients? A prospective cohort and in vitro study

Abstract Background Changes in the arginine metabolites asymmetric dimethyl-L-arginine (ADMA) and L-homoarginine and acute blood glucose concentrations have been shown to cause endothelial dysfunction and be independently associated with mortality in Intensive Care Unit (ICU) patients. The aim of th...

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Principais autores: Tien F. Lee, Sara Tommasi, Andrew Bersten, Leonie K. Heilbronn, Salvatore Sotgia, Angelo Zinellu, Ciriaco Carru, Arduino A. Mangoni, Morton G. Burt
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2023-04-01
coleção:Diabetology & Metabolic Syndrome
Assuntos:
Stress hyperglycemia ratio
Asymmetric dimethyl-l-arginine
l-homoarginine
Endothelial function
Critical illness
Dimethylarginine-dimethylaminohydrolase 1
Acesso em linha:https://doi.org/10.1186/s13098-023-01035-8
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