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EGFR-targeted photoimmunotherapy and its association with the immune microenvironment in locoregional recurrent head and neck squamous cell carcinoma

BackgroundEpidermal growth factor receptor (EGFR)-targeted photoimmunotherapy using cetuximab sarotalocan sodium (RM-1929) represents a novel therapeutic modality that induces selective tumor cell death and may influence the tumor immune microenvironment (TIME) in head and neck squamous cell carcino...

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Principais autores: Koichi Yoshizawa, Takahiro Tsujikawa, Peesit Leelasawatsuk, Mai Mohamed Bedeir, Yuna van der Aar, Tim de Martines, Saya Shibata, Hiroshi Ogi, Ryuhei Okada, Alisa Kimura, Hiroki Morimoto, Sumiyo Saburi, Shigeyuki Mukudai, Hikaru Nagao, Aya Miyagawa-Hayashino, Eiichi Konishi, Kyoko Itoh, Takahiro Asakage, Shigeru Hirano
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-04-01
coleção:Frontiers in Immunology
Assuntos:
EGFR
head and neck squamous cell carcinoma
immune microenvironment
locoregional recurrence
photoimmunotherapy
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1814205/full
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