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Chitosan Oligosaccharides Alleviate Colitis by Regulating Intestinal Microbiota and PPARγ/SIRT1-Mediated NF-κB Pathway

Chitosan oligosaccharides (COS) have been shown to have potential protective effects against colitis, but the mechanism underlying this effect has not been fully elucidated. In this study, COS were found to significantly attenuate dextran sodium sulfate-induced colitis in mice by decreasing disease...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Congcong Guo, Yue Zhang, Tao Ling, Chongjie Zhao, Yanru Li, Meng Geng, Sailun Gai, Wei Qi, Xuegang Luo, Liehuan Chen, Tongcun Zhang, Nan Wang
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2022-01-01
Schriftenreihe:Marine Drugs
Schlagworte:
chitosan oligosaccharides
ulcerative colitis
PPARγ
SIRT1
NF-κB
intestinal microbiota
Online-Zugang:https://www.mdpi.com/1660-3397/20/2/96
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