Efficient transfected liposomes co-loaded with pNrf2 and pirfenidone improves safe delivery for enhanced pulmonary fibrosis reversion

Pulmonary fibrosis (PF) is an interstitial lung disease with complex pathological mechanism, and there is currently a lack of therapeutics that can heal it completely. Using gene therapy with drugs provides promising therapeutic strategies for synergistically reversing PF. However, improving the int...

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Autori principali:	Xin Chang, Chang Liu, Yu-Mo Han, Qiu-Ling Li, Bin Guo, Hu-Lin Jiang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2023-06-01
Serie:	Molecular Therapy: Nucleic Acids
Soggetti:	MT: Delivery Strategies Pulmonary fibrosis transfected liposomes Gene delivery transfection efficiency Synergistic regulation
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2162253123000926
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