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Role of MicroRNA in Response to Ionizing Radiations: Evidences and Potential Impact on Clinical Practice for Radiotherapy

MicroRNAs (miRNA) are small, non-coding, RNAs with gene expression regulator roles. As an important class of regulators of many cellular pathways, miRNAs are involved in many signaling pathways and DNA damage repair processes, affecting cellular radiosensitivity. Their role has led to interest in on...

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Principais autores: Francesco Cellini, Alessio G. Morganti, Domenico Genovesi, Nicola Silvestris, Vincenzo Valentini
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2014-04-01
coleção:Molecules
Assuntos:
miRNA
miRNAs
microRNA
radiation
radiotherapy
resistance
review
tumor
DNA damage repair
radiosensibilization
Acesso em linha:http://www.mdpi.com/1420-3049/19/4/5379
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