Structural insights into broadly neutralizing antibodies elicited by hybrid immunity against SARS-CoV-2

Increasing spread by SARS-CoV-2 Omicron variants challenges existing vaccines and broadly reactive neutralizing antibodies (bNAbs) against COVID-19. Here we determine the diversity, potency, breadth and structural insights of bNAbs derived from memory B cells of BNT162b2-vaccinee after homogeneous O...

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Detalhes bibliográficos

Principais autores:	Mengxiao Luo, Biao Zhou, Eswar R. Reddem, Bingjie Tang, Bohao Chen, Runhong Zhou, Hang Liu, Lihong Liu, Phinikoula S. Katsamba, Ka-Kit Au, Hiu-On Man, Kelvin Kai-Wang To, Kwok-Yung Yuen, Lawrence Shapiro, Shangyu Dang, David D. Ho, Zhiwei Chen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2023-12-01
coleção:	Emerging Microbes and Infections
Assuntos:	SARS-CoV-2 Omicron BA.1 breakthrough infection hybrid immunity broadly neutralizing antibody memory B cell structural basis of antibody
Acesso em linha:	https://www.tandfonline.com/doi/10.1080/22221751.2022.2146538
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