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Toll-like receptor induced pro-interleukin-1β and interleukin-6 in monocytes are lower in healthy infants compared to adults.

Infants have long been known to have higher infectious diseases morbidity and mortality and suboptimal vaccination responses compared to older children and adults. A variety of differences in innate and adaptive immune responses have been described between these two groups. We compared Toll-like rec...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Daniel H Libraty, Lei Zhang, Marcia Woda, Luz P Acosta, Anamae Obcena, Job D Brion, Rosario Z Capeding
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2013-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:http://europepmc.org/articles/PMC3808280?pdf=render
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