Successful combination treatment with azacitidine and venetoclax as a bridging therapy for third allogenic stem cell transplantation in a patient with 11q23/MLL‐rearranged complex karyotype acute myeloid leukemia

Abstract Translocation t(6;11) occurs in approximately 5% of patients with acute myeloid leukemia (AML) corresponding to 11q23/mixed lineage leukemia (MLL) rearrangement. The AF6 gene on chromosome 6q27 is the fusion partner of the MLL gene on 11q23 in t(6;11), which results in a poor prognosis. The...

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Hauptverfasser:	Taro Edahiro, Hiroshi Ureshino, Ren Chishaki, Keita Fujino, Tatsuji Mino, Tetsumi Yoshida, Noriyasu Fukushima, Tatsuo Ichinohe
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2023-02-01
Schriftenreihe:	eJHaem
Schlagworte:	11q23/MLL‐rearranged acute myeloid leukemia azacitidine BCL‐2 venetoclax
Online-Zugang:	https://doi.org/10.1002/jha2.630
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