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Expression Analysis in Multiple Muscle Groups and Serum Reveals Complexity in the MicroRNA Transcriptome of the mdx Mouse with Implications for Therapy

MicroRNAs (miRNAs) are a class of small RNAs that regulate gene expression and are implicated in wide-ranging cellular processes and pathological conditions including Duchenne muscular dystrophy (DMD). We have compared differential miRNA expression in proximal and distal limb muscles, diaphragm, hea...

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Hlavní autoři: Thomas C Roberts, K Emelie M Blomberg, Graham McClorey, Samir EL Andaloussi, Caroline Godfrey, Corinne Betts, Thibault Coursindel, Michael J Gait, CI Edvard Smith, Matthew JA Wood
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2012-01-01
Edice:Molecular Therapy: Nucleic Acids
Témata:
Duchenne muscular dystrophy
mdx
microarray
microRNA
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2162253116300920
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