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Inhibition of matrix metalloproteinase-9 attenuates kidney fibrosis and cellular senescence in the transition from acute kidney injury to chronic kidney disease

Background The mechanisms underlying the progression of chronic kidney disease (CKD) following acute kidney injury (AKI) remain poorly understood. Senescent cells induce maladaptive repair have been identified as a significant contributor to CKD subsequent to AKI.Purpose The purpose of this study wa...

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Principais autores: Daoqi Shen, Liyu Lin, Yiqi Su, Jiarui Xu, Wuhua Jiang, Zhen Zhang, Yi Fang, Xiaoqiang Ding, Xialian Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2025-12-01
coleção:Renal Failure
Assuntos:
Acute kidney injury
AKI-to-CKD transition
cell senescence
fibrosis
Acesso em linha:https://www.tandfonline.com/doi/10.1080/0886022X.2025.2499897
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