Design and Synthesis of C-Terminal Modified Cyclic Peptides as VEGFR1 Antagonists

Previously designed cyclic peptide antagonist c[YYDEGLEE]-NH2 disrupts the interaction between vascular endothelial growth factor (VEGF) and its receptors (VEGFRs). It represents a promising tool in the fight against cancer and age-related macular degeneration. We described in this paper the optimiz...

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Detalhes bibliográficos

Principais autores:	Lei Wang, Nathalie Gagey-Eilstein, Sylvain Broussy, Marie Reille-Seroussi, Florent Huguenot, Michel Vidal, Wang-Qing Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2014-09-01
coleção:	Molecules
Assuntos:	VEGF VEGFR angiogenesis cyclic peptides
Acesso em linha:	http://www.mdpi.com/1420-3049/19/10/15391
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