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Transcriptomic analysis of spleen-derived macrophages in response to lipopolysaccharide shows dependency on the MyD88-independent pathway in Chinese giant salamanders (Andrias davidianus)

Abstract Background Gram-negative bacteria are the main bacterial pathogens infecting Chinese giant salamanders (Andrias davidianus; CGS) in captivity and the wild, causing substantial economic losses in the CGS industry. However, the molecular mechanisms underlying pathogenesis following infection...

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Tallennettuna:
Päätekijät: Jie Deng, Mengdi Han, Jingyu Gong, Hongying Ma, Yinting Hao, Cheng Fang, Han Zhang, Jia Li, Wei Jiang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMC 2024-10-01
Sarja:BMC Genomics
Aiheet:
Chinese giant salamander
Lipopolysaccharide
Macrophages
MyD88
Non-classical pathway
RNA-sequencing
Linkit:https://doi.org/10.1186/s12864-024-10888-w
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