Curcumin derivative C210 induces Epstein–Barr virus lytic cycle and inhibits virion production by disrupting Hsp90 function

Abstract Lytic induction therapy was devised to selectively combat malignancies associated with Epstein–Barr virus (EBV) by triggering viral reactivation from latency. At present, the major challenges of lytic induction therapy are to maximize reactivating efficiencies and meanwhile minimize infecti...

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Opis bibliograficzny

Główni autorzy:	Linli Chen, Xiaojing Guo, Wen Lin, Yingying Huang, Suling Zhuang, Qianfeng Li, Jianhua Xu, Shengnan Ye
Format:	Artigo
Język:	Inglês
Wydane:	Nature Portfolio 2024-11-01
Seria:	Scientific Reports
Hasła przedmiotowe:	Epstein–Barr virus Curcumin derivative Hsp90 inhibitor Lytic induction therapy Nasopharyngeal carcinoma Gastric carcinoma
Dostęp online:	https://doi.org/10.1038/s41598-024-77294-w
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