Disseminating cells in human oral tumours possess an EMT cancer stem cell marker profile that is predictive of metastasis in image-based machine learning

Cancer stem cells (CSCs) undergo epithelial-mesenchymal transition (EMT) to drive metastatic dissemination in experimental cancer models. However, tumour cells undergoing EMT have not been observed disseminating into the tissue surrounding human tumour specimens, leaving the relevance to human cance...

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Автори:	Gehad Youssef, Luke Gammon, Leah Ambler, Sophia Lunetto, Alice Scemama, Hannah Cottom, Kim Piper, Ian C Mackenzie, Michael P Philpott, Adrian Biddle
Формат:	Artigo
Мова:	Inglês
Опубліковано:	eLife Sciences Publications Ltd 2023-11-01
Серія:	eLife
Предмети:	cancer stem cell oral cancer metastasis machine learning multiplexed imaging prognosis
Онлайн доступ:	https://elifesciences.org/articles/90298
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