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An integrated analysis of MEN1 reveals its associations with clinical outcomes, cellular pathways, and the immune microenvironment

Abstract The menin protein, encoded by the Multiple Endocrine Neoplasia Type 1 (MEN1) gene, serves as a critical regulator of cellular processes in human cancers. While menin-targeted therapies are undergoing clinical investigation, a comprehensive pan-cancer analysis of MEN1's diagnostic, prognosti...

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Principais autores: Hao Li, Xinyu Gong, Yanwei Yao, Ping Bi, Qiang Li, Xiaoru Wang, Jian Peng
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-06-01
Serier:World Journal of Surgical Oncology
Fag:
MEN1
Pan-cancer
Prognosis
Immune microenvironment
Biomarker
Online adgang:https://doi.org/10.1186/s12957-026-04460-x
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