Transplantation Without Overimmunosuppression (TWO) study protocol: a phase 2b randomised controlled single-centre trial of regulatory T cell therapy to facilitate immunosuppression reduction in living donor kidney transplant recipients

Introduction Regulatory T cell (Treg) therapy has been demonstrated to facilitate long-term allograft survival in preclinical models of transplantation and may permit reduction of immunosuppression and its associated complications in the clinical setting. Phase 1 clinical trials have shown Treg ther...

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Hlavní autoři:	Susan Dutton, Ines Rombach, Joanna Black, Paul Harden, Giovanna Lombardi, William Petchey, Kathryn Wood, Fadi Issa, Matthew Oliver Brook, Joanna Hester, Matthew James Bottomley, Seetha Abdul-Wahab, Andrew Bushell, Peter Friend
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMJ Publishing Group 2022-04-01
Edice:	BMJ Open
On-line přístup:	https://bmjopen.bmj.com/content/12/4/e061864.full
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