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Membrane-active macromolecules resensitize NDM-1 gram-negative clinical isolates to tetracycline antibiotics.

Gram-negative 'superbugs' such as New Delhi metallo-beta-lactamase-1 (blaNDM-1) producing pathogens have become world's major public health threats. Development of molecular strategies that can rehabilitate the 'old antibiotics' and halt the antibiotic resistance is a promising approach to target th...

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Autori principali: Divakara S S M Uppu, Goutham B Manjunath, Venkateswarlu Yarlagadda, Jyothi E Kaviyil, Raju Ravikumar, Krishnamoorthy Paramanandham, Bibek R Shome, Jayanta Haldar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2015-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC4366164?pdf=render
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