Synthesis of new 2-{2,3-dihydro-1,4-benzodioxin-6-yl[(4-methylphenyl) sulfonyl]amino}-N-(un/substituted-phenyl)acetamides as α-glucosidase and acetylcholinesterase inhibitors and their in silico study

The aim of the present research work was to investigate the enzyme inhibitory potential of some new sulfonamides having benzodioxane and acetamide moieties. The synthesis was started by the reaction of N-2,3-dihydrobenzo[1,4]-dioxin-6-amine (1) with 4-methylbenzenesulfonyl chloride (2) in the presen...

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Библиографические подробности

Главные авторы:	Muhammad Athar Abbasi, Sajid Riaz, Aziz-ur- Rehman, Sabahat Zahra Siddiqui, Syed Adnan Ali Shah, Muhammad Ashraf, Muhammad Arif Lodhi, Farman Ali Khan
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
Серии:	Brazilian Journal of Pharmaceutical Sciences
Предметы:	Benzodioxane Acetamide Spectral analysis a-Glucosidase Acetylcholinesterase Molecular docking
Online-ссылка:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100518&lng=en&tlng=en
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