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Gene editing, metabolomics, network pharmacology strategies to explore terpenoid content and anti-TMV activity in NtSPS1 knockout Nicotiana tabacum

Abstract The content of terpenoids in tobacco can alter its resistance to TMV. NtSPS1, a pivotal structural gene in tobacco, is capable to regulate the terpenoid content. In this study, we investigated the effect of NtSPS1 knockout in HD on the content of terpenoids and the anti-TMV activity of this...

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Enregistré dans:
Auteurs principaux: Jia-Meng Dai, Jian-Duo Zhang, Xin Liu, Ling-Fang Zhang, Jin Wang, Yong Xu, Guang-Yu Yang, Jing Li, Ming-Li Chen, Qiu-Fen Hu
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2025-04-01
Collection:Scientific Reports
Sujets:
Nicotiana tabacum
CRISPR/Cas9
NtSPS1
Terpenoid
Network pharmacology
anti-TMV activities
Accès en ligne:https://doi.org/10.1038/s41598-025-98745-y
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