Neoantigen-specific T cell help outperforms non-specific help in multi-antigen DNA vaccination against cancer

CD4+ T helper antigens are essential components of cancer vaccines, but the relevance of the source of these MHC class II-restricted antigens remains underexplored. To compare the effectiveness of tumor-specific versus tumor-unrelated helper antigens, we designed three DNA vaccines for the murine MC...

詳細記述

書誌詳細

主要な著者:	Joanna Fréderique de Graaf, Tamara Pesic, Felicia S. Spitzer, Koen Oosterhuis, Marcel G.M. Camps, Iris Zoutendijk, Bram Teunisse, Wahwah Zhu, Tsolere Arakelian, Gerben C. Zondag, Ramon Arens, Jeroen van Bergen, Ferry Ossendorp
フォーマット:	Artigo
言語:	Inglês
出版事項:	Elsevier 2024-09-01
シリーズ:	Molecular Therapy: Oncology
主題:	MT: Regular Issue DNA vaccine cancer vaccine neoantigens personalized medicine immunotherapy
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2950329924000778
タグ:	タグ追加 タグなし, このレコードへの初めてのタグを付けませんか!