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The multiple roles of Ggt1-Cre in the generation of transgenic mice

Abstract The Cre/loxP system continues to serve as a well-established and widely adopted strategy for generating conditional gene knockout or knock-in mouse models, facilitating precise genetic manipulations. The Ggt1 gene, which exhibits specific expression in proximal tubular epithelial cells (TEC...

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Principais autores: Ze-Sen Feng, Jie Luo, Xiao-Cui Chen, Ping-Ping Zhao, Shi-Tong Qiu, Chun-Yu Wu, Xiao-Rong Huang, Bing-Chun Sun, Xiao-Jun Guo, Zhen-Nan Ye, Chen Yang, Hua-Feng Liu, Ji-Xin Tang
פורמט: Artigo
שפה:Inglês
יצא לאור: BMC 2026-01-01
סדרה:Cellular & Molecular Biology Letters
נושאים:
Cre/loxP system
CRISPR/Cas9
FAM134B
Gene knockout
Gene knock-in
Ggt1-Cre
גישה מקוונת:https://doi.org/10.1186/s11658-025-00844-1
תגים: הוספת תג
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