Dimethyl fumarate inhibits antibody-induced platelet destruction in immune thrombocytopenia mouse

Abstract Background Immune thrombocytopenia (ITP) is an autoimmune disease characterized as a low platelet count resulting from immune-mediated platelet destruction. Dimethyl fumarate (DMF) is widely applied for the treatment of several autoimmune diseases with immunosuppressive effect. However, whe...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Huan Tong, Yangyang Ding, Xiang Gui, Zengtian Sun, Guozhang Wang, Sixuan Zhang, Zhengqing Xu, Xiamin Wang, Xiaoqi Xu, Wen Ju, Yue Li, Zhenyu Li, Lingyu Zeng, Kailin Xu, Jianlin Qiao
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2021-08-01
Schriftenreihe:	Thrombosis Journal
Schlagworte:	Immune thrombocytopenia Dimethyl fumarate Macrophage Cell cycle Apoptosis
Online-Zugang:	https://doi.org/10.1186/s12959-021-00314-6
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