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Short-Term Transcriptomic Points of Departure Are Consistent with Chronic Points of Departure for Three Organophosphate Pesticides across Mouse and Fathead Minnow

New approach methods (NAMs) can reduce the need for chronic animal studies. Here, we apply benchmark dose (concentration) (BMD(C))–response modeling to transcriptomic changes in the liver of mice and in fathead minnow larvae after short-term exposures (7 days and 1 day, respectively) to several dose...

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Principais autores: Rubia Martin, Monique Hazemi, Kevin Flynn, Daniel Villeneuve, Leah Wehmas
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2023-09-01
coleção:Toxics
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Acesso em linha:https://www.mdpi.com/2305-6304/11/10/820
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