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Post-trial follow-up methodology in large randomised controlled trials: a systematic review

Abstract Background Randomised controlled clinical trials typically have a relatively brief in-trial follow-up period which can underestimate safety signals and fail to detect long-term hazards, which may take years to appear. Extended follow-up after the scheduled closure of the trial allows detect...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Rebecca Llewellyn-Bennett, Danielle Edwards, Nia Roberts, Atticus H. Hainsworth, Richard Bulbulia, Louise Bowman
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2018-05-01
Schriftenreihe:Trials
Schlagworte:
Methodology
Post-trial
Retention
Randomised controlled trial
Cost
Long-term
Online-Zugang:http://link.springer.com/article/10.1186/s13063-018-2653-0
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