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Thymic Regulatory T Cell Development: Role of Signalling Pathways and Transcription Factors

Regulatory T cells (Tregs) are a subset of CD4 T cells that are key mediators of immune tolerance. Most Tregs develop in the thymus. In this review we summarise recent findings on the role of diverse signalling pathways and downstream transcription factors in thymic Treg development.

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Mark Engel, Tom Sidwell, Ajithkumar Vasanthakumar, George Grigoriadis, Ashish Banerjee
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Wiley 2013-01-01
Цуврал:Clinical and Developmental Immunology
Онлайн хандалт:http://dx.doi.org/10.1155/2013/617595
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