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The transcriptional targets of mutant FOXL2 in granulosa cell tumours.

BACKGROUND: Despite their distinct biology, granulosa cell tumours (GCTs) are treated the same as other ovarian tumours. Intriguingly, a recurring somatic mutation in the transcription factor Forkhead Box L2 (FOXL2) 402C>G has been found in nearly all GCTs examined. This investigation aims to identi...

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Autori principali: Roseanne Rosario, Hiromitsu Araki, Cristin G Print, Andrew N Shelling
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2012-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC3460904?pdf=render
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