Glypican-3-Targeted Alpha Particle Therapy for Hepatocellular Carcinoma
Glypican-3 (GPC3) is expressed in 75% of hepatocellular carcinoma (HCC), but not normal liver, making it a promising HCC therapeutic target. GC33 is a full-length humanized monoclonal IgG1 specific to GPC3 that can localize to HCC in vivo. GC33 alone failed to demonstrate therapeutic efficacy when e...
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| Huvudupphov: | , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Utgiven: |
MDPI AG
2020-12-01
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| Serie: | Molecules |
| Ämnen: | |
| Länkar: | https://www.mdpi.com/1420-3049/26/1/4 |
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