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Picalm, a novel regulator of GLUT4-trafficking in adipose tissue

Objective: Picalm (phosphatidylinositol-binding clathrin assembly protein), a ubiquitously expressed clathrin-adapter protein, is a well-known susceptibility gene for Alzheimer's disease, but its role in white adipose tissue (WAT) function has not yet been studied. Transcriptome analysis revealed di...

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Main Authors: Jasmin Gaugel, Neele Haacke, Ratika Sehgal, Markus Jähnert, Wenke Jonas, Anne Hoffmann, Matthias Blüher, Adhideb Ghosh, Falko Noé, Christian Wolfrum, Joycelyn Tan, Annette Schürmann, Daniel J. Fazakerley, Heike Vogel
Format: Artigo
Language:Inglês
Published: Elsevier 2024-10-01
Series:Molecular Metabolism
Subjects:
Picalm
GLUT4-translocation
White adipose tissue
Type 2 diabetes
Obesity
miRNA
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877824001455
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