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Ginsenoside Rb1 alleviates endothelial dysfunction and vascular remodeling in preeclampsia via activation of the PI3K-Akt-eNOS pathway

Abstract Preeclampsia (PE) is a pregnancy-specific hypertensive disorder characterized by new-onset hypertension and proteinuria after 20 weeks of gestation. Endothelial dysfunction and abnormal placental vascular remodeling are central to its pathogenesis. Despite its significant impact on maternal...

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Hlavní autoři: Wen Jia, Wenli Wang, Baolian Zhang, Chengshu Wang, Xianghua Huang
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2026-03-01
Edice:Scientific Reports
Témata:
Preeclampsia
Rb1
Endothelial dysfunction
PI3K-Akt-eNOS
Placental remodeling
Vascular biology
On-line přístup:https://doi.org/10.1038/s41598-026-38411-z
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