Advances in polycythemia vera treatment with targeted therapies and clinical trials

Abstract Polycythemia vera (PV) is a chronic myeloproliferative disorder characterized by excessive red blood cell production, leading to a heightened risk of thrombosis, hemorrhage, and progression to myelofibrosis. While traditional therapies such as phlebotomy and hydroxyurea have been used for d...

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Main Authors: Doaa Hassanien, Rashid A. AlYafei, Omar H. Metwally, Izzaldin Alremawi, Abdulla Khalid Al-Kaabi, Mohamed Elahtem, Talal AL-Sayed, Mohamed A. Yassin
Format: Artigo
Sprog:Inglês
Udgivet: Springer 2025-10-01
Serier:Discover Oncology
Fag:
Polycythemia vera (PV)
Chronic myeloproliferative disorder (CMD)
Hepcidin agonists
MDM2 inhibitors
Histone deacetylase (HDAC) inhibitors
LSD1 inhibitors
Online adgang:https://doi.org/10.1007/s12672-025-03703-9
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