Critical evaluation of real‐world evidence of repurposable medicines in the Alzheimer's disease drug development pipeline using a target trial emulation

Abstract INTRODUCTION Repurposing Food and Drug Administration (FDA)‐approved drugs could accelerate treatment development for Alzheimer's disease (AD). METHODS Using the MarketScan claims database (2011 to 2020), we applied a trial emulation approach in two base cohorts: (1) individuals with mild c...

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Detalhes bibliográficos

Principais autores:	Reina Tonegawa‐Kuji, Ehud Karavani, Michael Danziger, Pengyue Zhang, Yuan Hou, Yadi Zhou, Marina Bykova, Andrew A. Pieper, Michal Rosen‐Zvi, Jeffrey Cummings, Feixiong Cheng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2026-01-01
coleção:	Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Assuntos:	Alzheimer's disease drug repurposing liraglutide real‐world evidence target trial emulation
Acesso em linha:	https://doi.org/10.1002/trc2.70193
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