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The interrelationship between APC/C and Plk1 activities in centriole disengagement

Summary Mother–daughter centriole disengagement, the necessary first step in centriole duplication, involves Plk1 activity in early mitosis and separase activity after APC/C activity mediates securin degradation. Plk1 activity is thought to be essential and sufficient for centriole disengagement wit...

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Detalles Bibliográficos
Principais autores: Toshiyuki Hatano, Greenfield Sluder
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists 2012-09-01
Series:Biology Open
Assuntos:
Acceso en liña:http://bio.biologists.org/content/1/11/1153
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