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64Cu-ATSM/64Cu-Cl2 and their relationship to hypoxia in glioblastoma: a preclinical study

Abstract Background Diacetyl-bis(N4-methylthiosemicarbazone), labeled with 64Cu (64Cu-ATSM) has been suggested as a promising tracer for imaging hypoxia. However, various controversial studies highlighted potential pitfalls that may disable its use as a selective hypoxic marker. They also highlighte...

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Hoofdauteurs: Elodie A. Pérès, Jérôme Toutain, Louis-Paul Paty, Didier Divoux, Méziane Ibazizène, Stéphane Guillouet, Louisa Barré, Aurélien Vidal, Michel Cherel, Mickaël Bourgeois, Myriam Bernaudin, Samuel Valable
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: SpringerOpen 2019-12-01
Reeks:EJNMMI Research
Onderwerpen:
Hypoxia
Brain tumors
Cu-ATSM
PET radiotracers
Copper transporters
Online toegang:https://doi.org/10.1186/s13550-019-0586-6
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