Inhibition of EZH2 Promotes Human Embryonic Stem Cell Differentiation into Mesoderm by Reducing H3K27me3

Mesoderm derived from human embryonic stem cells (hESCs) is a major source of the mesenchymal stem/stromal cells (MSCs) that can differentiate into osteoblasts and chondrocytes for tissue regeneration. While significant progress has been made in understanding of molecular mechanisms of hESC differen...

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Главные авторы:	Yongxin Yu, Peng Deng, Bo Yu, John M. Szymanski, Tara Aghaloo, Christine Hong, Cun-Yu Wang
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2017-09-01
Серии:	Stem Cell Reports
Предметы:	mesoderm mesenchymal stem cells EZH2 human ESCs osteoblast differentiation epigenetics histone methylation cell fate
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S2213671117303260
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