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CriSNPr, a single interface for the curated and de novo design of gRNAs for CRISPR diagnostics using diverse Cas systems

CRISPR-based diagnostics (CRISPRDx) have improved clinical decision-making, especially during the COVID-19 pandemic, by detecting nucleic acids and identifying variants. This has been accelerated by the discovery of new and engineered CRISPR effectors, which have expanded the portfolio of diagnostic...

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Principais autores: Asgar H Ansari, Manoj Kumar, Sajal Sarkar, Souvik Maiti, Debojyoti Chakraborty
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications Ltd 2023-02-01
coleção:eLife
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Acesso em linha:https://elifesciences.org/articles/77976
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