A nicotine-induced positive feedback loop between HIF1A and YAP1 contributes to epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma

Abstract Background Nicotine, an active ingredient in tobacco, can promote epithelial-to-mesenchymal transition (EMT) processes that enhance the aggressiveness of a number of human cancers. In the present study, we investigated whether cigarette smoke/nicotine drives EMT in pancreatic ductal adenoca...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Qiwen Ben, Wei An, Yunwei Sun, Aihua Qian, Jun Liu, Duowu Zou, Yaozong Yuan
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2020-09-01
Σειρά:	Journal of Experimental & Clinical Cancer Research
Θέματα:	Pancreatic ductal adenocarcinoma YAP1 Nicotine HIF1A Epithelial-to-mesenchymal transition
Διαθέσιμο Online:	http://link.springer.com/article/10.1186/s13046-020-01689-6
Ετικέτες:	Προσθήκη ετικέτας Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!