Porcine model of progressive cardiac hypertrophy and fibrosis with secondary postcapillary pulmonary hypertension

Abstract Background Meaningful translational large animal models for cardiac diseases are indispensable for studying disease mechanisms, development of novel therapeutic strategies, and evaluation of potential drugs. Methods For induction of heart failure, cardiac hypertrophy and fibrosis, a bare me...

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Κύριοι συγγραφείς:	Mariann Gyöngyösi, Noemi Pavo, Dominika Lukovic, Katrin Zlabinger, Andreas Spannbauer, Denise Traxler, Georg Goliasch, Ljubica Mandic, Jutta Bergler-Klein, Alfred Gugerell, Andras Jakab, Zsuzsanna Szankai, Levente Toth, Rita Garamvölgyi, Gerald Maurer, Frederic Jaisser, Faiez Zannad, Thomas Thum, Sándor Bátkai, Johannes Winkler
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2017-10-01
Σειρά:	Journal of Translational Medicine
Θέματα:	Cardiac hypertrophy PET-MRI imaging Aortic isthmus stenosis Translational large animal model Gene expression
Διαθέσιμο Online:	http://link.springer.com/article/10.1186/s12967-017-1299-0
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