Is N-methylacetazolamide a possible new therapy against ischemia-reperfusion injury?

The increase of intracellular Ca2+ concentration, produced principally by its influx through the L-type Ca2+ channels, is one of the major contributors to the ischemia-reperfusion injury. The inhibition of those channels in different experimental models was effective to ameliorate the post-ischemic...

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Bibliografiska uppgifter

Huvudupphov:	Alejandro Ciocci Pardo, Leandro A. Díaz Zegarra, Luisa F. González Arbeláez, Ernesto A. Aiello, Susana M. Mosca
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Frontiers Media S.A. 2023-08-01
Serie:	Frontiers in Pharmacology
Ämnen:	N-methylacetazolamide myocardial ischaemia reperfusion injury calcium L-type Ca2+ channel (CaL) cardioprotection
Länkar:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1223132/full
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