Poly(ADP-ribose)polymerase 2 is zinc-dependent enzyme and nucleosome reorganizer
Abstract Poly(ADP-ribose)polymerase 2 (PARP2) is a nuclear protein, DNA damage sensor and an emerging target for development of anti-cancer drugs. Previously it was discovered that PARP2 binds to nucleosomes; however, critical factors involved in this process remain unknown. We demonstrated that in...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer
2025-06-01
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| Serie: | Cellular and Molecular Life Sciences |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1007/s00018-025-05785-8 |
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