Sevoflurane Preconditioning Rescues PKMζ Gene Expression from Broad Hypoxia-Induced mRNA Downregulation Correlating with Improved Neuronal Recovery

Hypoxia due to stroke is a major cause of neuronal damage, leading to loss of cognition and other brain functions. Sevoflurane preconditioning improves recovery after hypoxia. Hypoxia interferes with protein expression at the translational level; however, its effect on mRNA levels for neuronal prote...

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Autors principals:	Joan Y. Hou, Kim D. Allen, A. Iván Hernandez, James E. Cottrell, Ira S. Kass
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2025-01-01
Col·lecció:	NeuroSci
Matèries:	anesthesia sevoflurane hypoxia protein kinase mRNA anti-apoptotic mRNA transcriptional downregulation
Accés en línia:	https://www.mdpi.com/2673-4087/6/1/9
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