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In vitro and in vivo protective efficacies of antibodies that neutralize the RNA N-glycosidase activity of Shiga toxin 2

<p>Abstract</p> <p>Backgound</p> <p>Shiga toxin 2 (Stx2), one of two Stx liberated by Stx-producing <it>Escherichia coli</it>, is composed of an A subunit monomer and a B subunit pentamer, and is directly linked with hemolytic uremic syndrome in children. The pentameric B subunit binds to its cell s...

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Principais autores: Tzipori Saul, Lee Jongo, Singh Pradeep, Chapman-Bonofiglio Susan, Jeong Kwang-il, Sheoran Abhineet S
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2010-03-01
Series:BMC Immunology
Acceso en liña:http://www.biomedcentral.com/1471-2172/11/16
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