Hemizygous Deletion on Chromosome 3p26.1 Is Associated with Heavy Smoking among African American Subjects in the COPDGene Study.

Many well-powered genome-wide association studies have identified genetic determinants of self-reported smoking behaviors and measures of nicotine dependence, but most have not considered the role of structural variants, such as copy number variation (CNVs), influencing these phenotypes. Here, we in...

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Autors principals:	Ferdouse Begum, Ingo Ruczinski, John E Hokanson, Sharon M Lutz, Margaret M Parker, Michael H Cho, Jacqueline B Hetmanski, Robert B Scharpf, James D Crapo, Edwin K Silverman, Terri H Beaty
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2016-01-01
Col·lecció:	PLoS ONE
Accés en línia:	http://europepmc.org/articles/PMC5053531?pdf=render
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