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Genetic and biochemical characterizations of Zika virus NS2A protein

Zika virus (ZIKV) can cause devastating congenital Zika syndromes in pregnant women and Guillain-Barre syndrome in adults. Understanding the molecular mechanism of ZIKV replication is essential for antiviral and vaccine development. Here we report the structural and functional characterization of ZI...

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Principais autores: Xianwen Zhang, Xuping Xie, Jing Zou, Hongjie Xia, Chao Shan, Xinwen Chen, Pei-Yong Shi
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2019-01-01
Serier:Emerging Microbes and Infections
Fag:
Zika virus
flavivirus replication
virion assembly
flavivirus NS2A
membrane topology
Online adgang:https://www.tandfonline.com/doi/10.1080/22221751.2019.1598291
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